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Urea USP

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Urea USP
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Urea USP
CAS No. 57-13-6

Urea is a byproduct of protein metabolism and a normal metabolic constituent in biological organisms. It is a naturally occurring compound, appearing in our urine and that of all mammals, but it is manufactured synthetically on a large scale worldwide as it is used in many industrial processes.

With its ability to disrupt the noncovalent bonds in proteins, urea can be a powerful protein denaturant.  This keratolytic property can be exploited in topical preparations containing high amounts of urea where it is used to help with the rapid turnover of skin cells leading to the improvement of dry scaly skin.  Urea is both a humectant and moisturizer that promotes rehydration of the skin and helps to replenish natural urea content of the skin lost with cleansing.  While the mechanism of action remains unclear, Urea, applied topically, acts as an anti-inflammatory agent on dermatalogically compromised skin.

Urea is readily soluble: 1 gram dissolves in 1 ml water, 10ml of 95% alcohol or 2 ml of glycerol.


  • Moisturization
  • Replenish natural skin urea lost to cleansing
  • Exfoliation

Use In

  • Creams and lotions for dry skin
  • Sun and after-sun lotions
  • Shampoos and body washes
  • Body scrubs
  • Cracked heal and elbow moisturizers

Formulation Guidelines:

  • Add to the water phase of formulations
  • Not heat sensitive

Our Urea meets USP specifications, but it is considered a cosmetic grade material once we repackage it.

This is a cosmetic raw material and is meant for external use only in cosmetic formulations.  As with all of our materials, it should not be taken internally.

Recommended Usage: 2 - 15%, up to 40%

Appearance: White to off-white crystal
Odor: Slight ammoniacal odor
pH 5% sol.: 7.2
Solubility: Water soluble, also partially soluble in ethanol and glycerol
Shelf Life: 2 Years

Country of Origin: Mexico

INCI: Urea

Shipping Information: HS Code 3102100000


Here you will find Safety Data Sheets (SDS) and Technical Data Sheets. The files are in PDF format. To access a file, click on the relevant button or the file name. For your convenience, it will open up in a new browser window.

Please note: You must have Acrobat Reader to view the files listed here. If necessary, the Acrobat Reader link will directed you to a page where it can be downloaded.

Technical Data

Safety Data Sheet (SDS)



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