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Tetrahexyldecyl Ascorbate




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Tetrahexyldecyl Ascorbate
CAS No. 183476-82-6


Tetrahexyldecyl Ascorbate is a very stable, oil-soluble Vitamin C ester which has anti-oxidant activity, inhibiting lipid peroxidation. Topical use can mitigate the damaging effects of UV exposure. Studies have shown it to stimulate collagen production as well as clarifying and brightening the skin by inhibiting melanogenesis (the production of pigment) thereby promoting a more even skin tone. Unlike ascorbic acid, it will not exfoliate or irritate skin.

Properties

  • At 0.1% reduces melanin synthesis by 80%
  • At 10% eliminated age spots in 16 weeks
  • At 3% in vivo reduces Delta-L value by 15% vs. placebo (22 people), a way to measure whitening effect
  • At 0.1% in vitro increases collagen by 50%
  • Tested at 10% in vivo to treat acne with 80% of patients (12 people) satisfied with results
  • Increases collagen synthesis at least twice as much as ascorbic acid
  • Inhibits MMP-2 and MMP-9 over e time better than ascorbic acid
  • decreased 80-OHdG induced by UV-A
  • decreased p53 expression induced by UV-B
  • Protects the cells against UV-B better than other esters of Vitamin C
  • Works synergistically with Thiotaine as both penetrate the cells for anti-oxidant activity

Formulation Guidelines

  • Should be added into the oil phase of formulations at temperatures below 80°C (176°F)
  • Can be used in formulas with a pH range of 3 to 6.
  • Approved as a quasi-drug in Korea at 2%, and in Japan at 3%
  • Approved as a functional ingredient for whitening at 2% in Korea

Typical Usage: 0.5-3%, can be used up to 10%
Appearance: Clear to pale yellow viscous liquid
Storage: Store in a cool dry place, avoid freezing
Solubility: Oil Soluble
Country of Origin:  Japan


INCI: Tetrahexyldecyl Ascorbate

Caution: Do not directly apply onto your skin.
This product should be added to a formulation at the recommended usage rate.

 

Disclaimer
Statements contained herein have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional skin care provider.

California Prop 65 Statement: The following statement is made in order to comply with the California Safe Drinking Water and Toxic Enforcement Act of 1986. This product is not known to the State of California to cause cancer, birth defects or other reproductive harm.

Here you will find Safety Data Sheets (SDS) and Technical Data Sheets. The files are in PDF format. To access a file, click on the relevant button or the file name. For your convenience, it will open up in a new browser window.

Please note: You must have Acrobat Reader to view the files listed here. If necessary, the Acrobat Reader link will directed you to a page where it can be downloaded.

Technical Data

 
Tetrahexyldecyl Ascorbate Fact Sheet

 

Safety Data Sheet (SDS)

Tetrahexyldecyl Ascorbate SDS

 

Lotioncrafter formulas in which this ingredient appears are listed below. Formulas are used as a means to provide basic formulating information and guidance in the use of ingredients Lotioncrafter supplies. Formulations are provided in percentages, grams and ounces. Most create a batch size of 1000g (33 ounces). Because percentages are provided, they can be sized up or down with ease.

The files are in PDF format. To access a file, click on the relevant button or the file name. For your convenience, it will open up in a new browser window.

Please note: You must have Acrobat Reader to view the files listed here. If necessary, the Acrobat Reader link will directed you to a page where it can be downloaded.

Formulations
Double C Serum
C&E Intensive Serum
CoQ10 Moisturizer with Polypeptide Complex
Time DefyTM Facial Serum

By accessing this formulation you acknowledge that it is your responsibility to ensure formulation integrity and freedom to practice and that the information herein is provided with no warranties express or implied. Ensuring suitability and stability is your responsibility in every respect and should include doing appropriate formula stability and preservative efficacy testing as well as appropriate patent search and analysis.


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