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Leuphasyl




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Leuphasyl
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Leuphasyl®

Leuphasyl® is a new peptide developed by Lipotec to reduce expression wrinkles and that offers two advantages:

  • A new and alternative in vitro mechanism to fight expression wrinkles
  • An additive / synergistic effect to complement the action of Argireline® and other peptides

Leuphasyl®’s mechanism mimics in vitro the natural mechanism of enkephalins: it couples to the enkephalin receptor, on the outside of the nerve cells. When Leuphasyl® couples to the receptor, a conformational change initiates a cascade inside the neuron that results in a decrease of its excitability: the nerve cell’s activity is “turned down” and the release of acetylcholine is modulated. Muscle contraction will be relaxed and therefore, expression wrinkles will be diminished.

Properties and Applications

Leuphasyl® reduces the depth of wrinkles on the face caused by the contraction of muscles of facial expression, especially in the forehead and around the eyes.

Leuphasyl® targets in vitro the wrinkle-formation mechanism of expression wrinkles in a new way, offering an alternative to peptides like Argireline®.

Leuphasyl® can be incorporated in cosmetic formulations such as emulsions, gels, serums, etc., where removal of the deep lines or wrinkles in the forehead or around the eye area is desired.

Incorporation: Leuphasyl® should be processed below 40°C (104°F) at the final stage of the manufacturing process.


Recommended Usage Rate: 3 - 10%


Appearance: Colorless, translucent solution
Solubility: Water Soluble
pH (as supplied): 2.0 - 5.0
Preservative: Caprylyl Glycol at 0.5.6%
Manufacturer: Lipotec
Country of Origin: Spain
Storage: Leuphasyl® should be stored in the original sealed containers protected from light in a clean and cool place and is best kept in the refrigerator. In rare cases, refrigerated storage of Leuphasyl® can cause precipitation of the preservative. This does not affect the integrity of the product.  If stored properly, Leuphasyl® should have a shelf life of at least 18 months.

INCI: Water (and) Glycerin (and) Pentapeptide-18

Shipping Information: HS Code  2924190000

This product should be added to a formulation at the recommended usage rate.

Disclaimer
Statements contained herein have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat and cure or prevent disease. Always consult with your professional skin care provider.

California Prop 65 Statement: The following statement is made in order to comply with the California Safe Drinking Water and Toxic Enforcement Act of 1986. This product is not known to the State of California to cause cancer, birth defects or other reproductive harm.

Here you will find Safety Data Sheets (SDS) and Technical Data Sheets. The files are in PDF format. To access a file, click on the relevant button or the file name. For your convenience, it will open up in a new browser window.

Please note: You must have Acrobat Reader to view the files listed here. If necessary, the Acrobat Reader link will directed you to a page where it can be downloaded.

Technical Data
Leuphasyl Brochure
Leuphasyl Technical Presentation
Leuphasyl Marketing Presentation

Safety Data Sheet (SDS)
Leuphasyl SDS

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News
05-25-2018
So that our staff may enjoy the Memorial Day Holiday, Lotioncrafter's offices will be closed on Monday, May 28th. We will reopen on Tuesday, May 29th. During this time, we will not be returning phone calls or email messages. Shipping will resume on Tuesday, May 29th. Orders, emails and phone calls will be handled in the order received, as best we are able. Please expect some delays as we work through the holiday backlog! We also cannot guarantee changes to orders will be seen before orders have shipped, those that we do catch, will be held back to adjust, which will mean a shipping delay. We appreciate your understanding. Have a safe and happy Memorial Day!

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